Child Autism: Genetics & Environment

Child Autism Dubai | Is It Caused By Genetics? Or The Environment? It Is A Dance Between Both

Child autism Dubai: Genetic vulnerability, metabolic disruption or vaccinations & insights into biology of autism

Child autism Dubai: Autism is a social and communication disorder that is gaining increasing importance as the incidence of autism worldwide spirals out of control. It was thought to be a genetic developmental disorder which was lifelong and only treatable not curable.

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With the 600% increase in its incidence over two decades intense research has been initiated to show some startling results. We know genetics don’t cause epidemics. The role of environment in the causality of autism is gaining ground.

Present research points to an interaction between genetic vulnerability and environmental triggers. This interaction occurs mostly in the first two years of life as the developing brain is assaulted with toxins.

Child autism Dubai: Review of genetic vulnerability to autism

Genetic vulnerability causes a reduced ability to detoxify toxins in a child. The mitochondria or the powerhouses of cells are the most vulnerable. The inability to detoxify toxins makes cells more vulnerable.

So what are these toxins and how do they act on the cell? Research indicates that children with autism have higher levels of heavy metals in their body. They have increased the amount of inflammation as well as deregulated immunity.

Their guts are more prone to damage caused by altered microbial flora and fungal infections. All this causes disruption in the gut-blood-brain barrier causing brain inflammation.

Child Autism Dubai | https://www.pediatriciandubai.blog/autism-symptoms-in-children-dubai/children-with-autism-dubai/child-autism-dubai/ Is It Caused By Genetics? Or The Environment? It Is A Dance Between Both

Child Autism Dubai

Child autism Dubai: To receive information to help your child fill in your name and email ID in the form on the right

Child autism Dubai: What causes metabolic disruption?

The resultant metabolic disruption is caused by oxidative stress, mitochondrial dysfunction, and dysbiosis.

Oxidative stress is caused by oxygen that produces reactive species like peroxidize and free radicals. We know that radiation, smoking, pollution, lack of certain nutrients can cause oxidative stress. The free radicals cause cell damage and death.

The body has the ability to detoxify toxins and free radicals. One of the most important processes to achieve this is through the production of ‘Reduced Glutathione’ The process is called the ‘Methylation Sulphation’ cycle.

Various metabolic reactions convert amino acid Methionine into Reduced Glutathione in several stepwise processes. Each step requires catalysts like vitamins B6 or magnesium or others.

Hence treatment includes giving these supplement in high doses to stimulate the process. Cytokines are indicators of inflammations in the body. Children with autism have higher levels of cytokines compared to healthy controls and also when compared to children with other developmental delays and mental handicaps.

Children with autism have a higher incidence of allergies, infections, and immune problems. Children born to mothers with  Rheumatoid arthritis during pregnancy had higher rates of ASD.

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Child autism Dubai: Is autism genetic?

It is certain that there is a strong genetic element. However, studies have shown many cases of “spontaneous” genetic mutation which are not inherited.

In addition, studies have shown that parents from families with autistic members are more likely to have autistic children, and families with one autistic child are at increased risk of having another.

Nonetheless, it is becoming increasingly clear that autism is epigenetic and genes interact with the environment to cause problems.

Child autism Dubai: Do vaccines cause autism?

Two theories link autism and vaccines. The first theory suggests that the MMR (Mumps-Measles-Rubella) vaccine may cause intestinal problems leading to the development of autism.

The second theory suggests that a mercury-based preservative called thimerosal, used in some vaccines could be connected to autism. The medical community has soundly refuted these theories, but a very passionate group of parents and researchers continue to disagree, based on anecdotal evidence.

Child Autism Dubai | https://www.pediatriciandubai.blog/autism-symptoms-in-children-dubai/children-with-autism-dubai/child-autism-dubai/ Is It Caused By Genetics? Or The Environment? It Is A Dance Between Both

Child Autism Dubai

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Child Autism: Genetics & Environment was last modified: February 13th, 2018 by Wilma Gervacio

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